Input Page | Downloads | Help/Info 

Confidence viewConfidence view 
Evidence viewEvidence view 
Actions viewActions view 
InteractiveInteractive advanced
Show stereo-isomersShow stereo-isomers 
Combine stereo-isomersCombine stereo-isomers 
Chemical linksChemical links 
Add nodesAdd nodes 
Remove nodesRemove nodes 
SaveSave 
  chromium (Homo sapiens) - STITCH interaction network
 

This is the confidence view. Stronger associations are represented by thicker lines.
Protein-protein interactions are shown in blue, chemical-protein interactions in green and interactions between chemicals in red.

 
   
Your Input:
chromium
An element with atomic symbol Cr, atomic number 24, and atomic weight 52. (52.0 g/mol)
(Homo sapiens)
Predicted Functional Partners:
POLB
polymerase (DNA directed), beta; Repair polymerase. Conducts "gap-filling" DNA synthesis in a s [...] (335 aa)
0.956
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
0.896
HMOX1
heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge [...] (288 aa)
0.882
HMOX2
heme oxygenase (decycling) 2; Heme oxygenase cleaves the heme ring at the alpha methene bridge [...] (316 aa)
0.860
NQO1
NAD(P)H dehydrogenase, quinone 1; The enzyme apparently serves as a quinone reductase in connec [...] (274 aa)
0.859
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
0.834
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); In addit [...] (660 aa)
0.824
TIMP1
TIMP metallopeptidase inhibitor 1; Complexes with metalloproteinases (such as collagenases) and [...] (207 aa)
0.824
INSR
insulin receptor; This receptor binds insulin and has a tyrosine-protein kinase activity. Isofo [...] (1382 aa)
0.823
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1; Sodium/sulfate cotransporter th [...] (595 aa)
0.811
 
  Views:            
   Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: high (89%)